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White Sox at Rays prediction: Odds, expert picks, starting pitchers, betting trends, and stats for July 22

Its Tuesday, July 22 and the White Sox (36-65) look to extend their winning streak to a season-high five games tonight in Tampa against the Rays (52-49).

Davis Martin is slated to take the mound for Chicago against Drew Rasmussen for Tampa Bay.

The Sox jumped on Shane Baz early scoring three in the second inning and three more in the third. Brooks Baldwin went yard in the second to start the fireworks. Six pitchers limited the Rays to five hits on the night as Chicago equaled their season-high with a fourth consecutive win.

Lets dive into Game 2 of the series and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch White Sox at Rays

Date: Tuesday, July 22, 2025
Time: 7:35PM EST
Site: George M. Steinbrenner Field
City: Tampa, FL
Network/Streaming: CHSN, FDSNSUN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the White Sox at the Rays

The latest odds as of Tuesday:

Moneyline: White Sox (+188), Rays (-228)
Spread: Rays -1.5
Total: 8.0 runs

Probable starting pitchers for White Sox at Rays

Pitching matchup for July 22, 2025: Davis Martin vs. Drew Rasmussen
- White Sox: Davis Martin (2-7, 3.79 ERA)
  Last outing: June 12 at Houston - 6IP, 4ER, 7H, 2BB, 5Ks
- Rays: Drew Rasmussen (7-5, 2.86 ERA)
  Last outing: July 11 at Boston - 2IP, 1ER, 3H, 1BB, 1K

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of White Sox at Rays

The Rays have won 26 of 49 games following a defeat
The Under is 33-27-2 in the White Sox’s games against American League teams this season
The White Sox have covered in 4 of their last 5 road games and they are profiting 1.63 units in those 5
Miguel Vargas has homered in back-to-back games and is now 5-13 over his last 3 games
Andrew Benintendi has at least 1 hit in 4 of his last 5 games (8-18) including 1 HR and 3 RBI

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the White Sox and the Rays

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Tuesday’s game between the White Sox and the Rays:

Moneyline: NBC Sports Bet is recommending a play on the Tampa Bay Rays on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
Total: NBC Sports Bet is leaning towards a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

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