Bruker and 10x Genomics settle patent dispute

Ross Law

Wed, May 14, 2025, 1:32 PM 2 min read

Bruker and 10x Genomics have agreed to settle a patent dispute relating to products originally developed by Nanostring, a company Bruker acquired in 2024.

Under the settlement, whose financial terms have not been disclosed, the two companies have entered into global cross-license agreements for their patents. Additionally, all ongoing lawsuits and administrative proceedings in the US, Germany, and before the European Unified Patent Court, will be withdrawn.

Filed by 10x in 2023, the initial lawsuit asserted that Nanostring’s GeoMx Digital Spatial Profiler, a product that profiles the spatial distribution of RNA and protein expression across a tissue sample, infringed on seven patents. In November 2023, the district court of Delaware sided with 10x.

Nanostring, a publicly listed company when the lawsuit was filed, went bankrupt in February 2024. Bruker acquired the company a month later for $392.6m, and inherited the lawsuit.

On 23 December 2024, Delaware’s district court issued its ruling on post-trial motions, in which damages of $31.6m were upheld, yet enhanced damages requested by 10x were declined. The final motion, an injunction request by 10x, was granted by the court, meaning that sales of GeoMx products to new customers in the US would be halted.

At the time, Todd Garland, Bruker spatial biology division’s president, said the company would “promptly seek a stay” on any injunction ordered and looked forward to the appeal of its case being heard by the US Court of Appeals for the Federal Circuit.

Commenting on the settlement agreement, Mark Munch, president of the Bruker Nano Group, said the company was happy to have the “distraction and expense” of the legal cases behind it.

“We’re pleased that we have reached a worldwide settlement with 10x, putting an end to all litigation between us,” Munch said.

“This is a great outcome for the scientific community, who can continue their work using Bruker’s CosMx and GeoMx spatial biology platforms without concern that litigation could interfere with their advancements in oncology, neurobiology, and other fields of research.”

"Bruker and 10x Genomics settle patent dispute" was originally created and published by Medical Device Network, a GlobalData owned brand.

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